Understanding
Neuropathy

Peripheral neuropathy is a general term for nerve damage anywhere except in the brain and spinal cord. When you experience neuropathy, it can manifest as tingling, numbness, and all sorts of uncomfortable sensations1. Managing neuropathy requires care and patience. Whether it’s through daily pills, therapy, or lifestyle changes, we’re here to guide you on this journey and empower you to regain control over the nerves that are acting out.

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Step 1: Understanding Your Nerves

Your nerves don’t want to hurt you, but pain is how they communicate that they’re damaged. The stinging and tingling sensations are actually your nerves asking for attention and help. Your body is talking to you, but are you listening? Let’s dive into the symptoms of neuropathy so you know what to be in tune with.

Recognizing The Behaviors Of Neuropathic Nerves

When it comes to neuropathy, understanding the signs and symptoms is key to early detection and effective management. While neuropathic symptoms can vary depending on the underlying cause and the nerves affected, there are some common behaviors that may indicate neuropathy is at play1:

  • Tingling or prickling sensations (paresthesia)
  • Numbness or loss of sensation
  • Muscle weakness or coordination difficulties
  • Pain that could be described as burning, stabbing, or shooting

These symptoms may vary in onset and intensity but are common indicators of nerve damage. It’s important to seek medical evaluation and get a proper diagnosis so you can properly manage your neuropathy. With early recognition and intervention, you can take proactive steps towards improving your quality of life.

Causes of Neuropathy

In addition to recognizing the symptoms of neuropathy, it’s also important to understand the risk factors and causes of neuropathy. Though lifestyle choices can lead to neuropathy, sometimes health conditions and physical traumas can be to blame.

Here are some of the known causes of nerve damage2,3:

  • Diabetes – It’s believed that the reason diabetes is linked to nerve damage is because of high blood sugar levels.
  • Vitamin Deficiency – Insufficient levels of B vitamins are linked to neuropathy.
  • Alcoholism – Consistent high intake of alcohol leads to lower amounts of vitamins which may cause neuropathy.
  • Diseases – Certain infections, health conditions, and diseases can cause neuropathy.
  • Medications – Some medications and antibiotics come with the risk of nerve damage as a side effect.
  • Injuries – Falls, crashes, and frequent pressure can damage nerves.

Step 2: Loving Your Nerves

Once you know why your nerves are crying out for attention, you can start to address their needs. This can look like changing your lifestyle, adjusting your diet, taking medications to address the underlying causes, or supplementing nutrient deficiencies4. In many cases, the proper course of action can bring you relief and also improve nerve health. However, in more severe cases, surgery may be suggested5. No matter how you choose to care for your nerves, we recommend that you consult with a doctor and monitor your condition.

Finding Science-Backed Nerve Supplements

Before we get to our top recommended supplements for neuropathy (see below), let’s take a look at some of the most common ingredients for supporting nerve health.

  • B Vitamins – Deficiencies in vitamins B1, B6, and B12 are linked to neuropathy6.
  • Alpha Lipoic Acid – Several clinical studies have found ALA to be an effective ingredient for managing neuropathy*. This ingredient has not produced adverse reactions and is considered safe7.
  • Boswellia Serrata – Researchers found that a compound in Boswellia helped to repair damaged sciatic nerves in rats and helped to enhance nerve regeneration8.
  • Acetyl L-Carnitine – This ingredient has been found to exhibit neuroprotective properties that are beneficial for cases of neuropathy9.

While these are all studied ingredients, it is unlikely that you will find a formula with all four of these ingredients, and you will typically find other ingredients added to nerve health supplements. However, we suggest looking for some of these top ingredients when choosing an neuropathy supplement. Different supplements will contain different ingredients that work together differently. For example, a supplement that contains the 3 of the top most common ingredients with a blend of other studied ingredients can be beneficial for managing neuropathy10.

Step 3: Practicing Patience

Managing neuropathy is a marathon, not a sprint. It’s going to take time. Some days may be frustrating but it’s important to remain consistent. Stick with your lifestyle and diet changes to give them a real chance. Additionally, if you choose to take a supplement, remember that it is not a magic pill and it may take some time before you start to see results. We recommend choosing supplements that have a money-back guarantee because they allow you to try the supplement and ensure that you’re not out of pocket if it doesn’t work for you. 

Our Top 5 Favorite Neuropathy Supplements For Promoting Nerve Health:

#1
Approved Science Nervprin

What Do We Like?

  • Contains researched vegan ingredients.
  • Includes vitamins for replenishing deficiencies.
  • Includes BioPerine® for increased bioavailability and absorption11,12.
  • Customers have reported experiencing pain relief10.
  • Cost-saving purchasing options.
  • 60-day money-back guarantee on both used and unused bottles.*
  • Third-party tested.
  • Manufactured in a cGMP-certified facility.

The Downside

  • Sells out fast.

Our Takeaway

Nervprin is a nerve health supplement from the well-established brand Approved Science. The manufacturer did an excellent job of putting together a formula that is backed by scientific research. It contains bioactive B Vitamins, a Magnesium complex, ALA, Boswellia, Corydalis, and BioPerine. The product has been available for several years and has accumulated many positive reviews8. It provides great value for your money, especially if you are looking for long-term nerve support and take advantage of their package deals. For example, a 3-month supply is only $98.85, and the 6-month supply offers greater savings*. Lastly, with a 60-day money-back guarantee you are pretty much covered. All in all, this is a product that we highly recommend.

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The reviews and rankings presented on this site are based on the MySupplementNews ranking system and opinions. Your experience may vary.

#2
Free Life Labs NerveReverse

What Do We Like?

  • Contains bioavailable, researched ingredients.
  • Includes vitamins for replenishing deficiencies.
  • Cost-saving purchasing options.
  • Customers have reported experiencing pain relief13.
  • Third-party tested.
  • Manufactured in a cGMP-certified facility.
  • 6-month money-back guarantee with conditions (see below)*.

The Downside

  • Not vegan
  • Doesn’t contain BioPerine® for increased absorption.

Our Takeaway

NerveReverse is the only supplement by Free Life Labs. It has a simpler formula than Nervprin, with only B Vitamins, Vitamin D3, and ALA. The formula is backed by science and the product website even provides links to relevant clinical studies. The product became available on Amazon in late 2017 and the reviews show that customers usually like the product14. Priced at $134.95* for three months, in the long run it’s a little more expensive than Nervprin but still decently priced. The money-back guarantee is valid for 6 months, but you are only eligible for it if you take the product for 90 consecutive days.

The reviews and rankings presented on this site are based on the MySupplementNews ranking system and opinions. Your experience may vary.

#3
Wise Help Neuropathy Support

What Do We Like?

  • Contains researched ingredients.
  • Includes vitamins for replenishing deficiencies.
  • Customers have reported experiencing pain relief15.
  • Manufactured in a cGMP-certified facility.

The Downside

  • Does not disclose ingredient amounts due to a proprietary blend.
  • Doesn’t contain BioPerine® for increased absorption.
  • No cost-saving purchasing options.
  • No money-back guarantee.

Our Takeaway

Wise Help Neuropathy Support combines the B Vitamins with Magnesium and a proprietary blend containing Acetyl L-Carnitine, ALA, Ashwagandha, and Oat Straw extract. We wish that Wise Help had chosen transparency over the use of a proprietary blend. A fully transparent label would provide customers with more knowledge about what exactly they are putting in their bodies, in case they need to take multiple supplements. The product has been available since 2021 and like our other favorites has also collected many positive reviews16. Wise Help Neuropathy Support is marginally cheaper than our top picks but there is no money-back guarantee.

The reviews and rankings presented on this site are based on the MySupplementNews ranking system and opinions. Your experience may vary.

#4
NerveSpa Nerve Rebuilder Formula

What Do We Like?

  • Contains researched ingredients.
  • Includes vitamins for replenishing deficiencies.
  • Manufactured in a cGMP-certified facility.

The Downside

  • Contains a proprietary blend.
  • Doesn’t contain BioPerine® for increased absorption.
  • No customer reviews.
  • No cost-saving purchasing options.
  • No money-back guarantee.
  • Not vegan.

Our Takeaway

NerveSpa is a small brand with a few different products for individuals with neuropathy. Nerve Rebuilder Formula provides select B Vitamins (B1, B12, and B6) as well as amino acids and botanicals. This product is decently priced but there is no money-back guarantee to display the manufacturer’s confidence in the product and we were unable to find customer reviews.

The reviews and rankings presented on this site are based on the MySupplementNews ranking system and opinions. Your experience may vary.

#5
Nuphoria Gold Original Formula

What Do We Like?

  • Contains bioavailable, researched ingredients.
  • Includes vitamins for replenishing deficiencies.
  • Some positive reviews17.
  • Manufactured in a cGMP-certified facility.

The Downside

  • Contains a proprietary blend.
  • Doesn’t contain BioPerine® for increased absorption.
  • No cost-saving purchasing options.
  • No money-back guarantee.
  • Not vegan.

Our Takeaway

Nuphoria is a nerve-centered brand with the slogan “The Nerve Experts”. The Nuphoria Gold Original Formula provides bioactive B Vitamins, Calcium, Manganese, Chromium, R-ALA, and a Mushroom powder. Customers have reported that this product helped to reduce their pain18. This product is the most expensive on our list and does not offer a money-back guarantee.

The reviews and rankings presented on this site are based on the MySupplementNews ranking system and opinions. Your experience may vary.